The great revolution of the twenty-first century in new technologies has led terrorist groups to use less expensive and easier weapons and methods to achieve their goals in line with these developments. A clear example of them, is the use of biological weapons and the application of biological threats. The importance of bioterrorism threats and their extensive works led to increased international attention to this phenomenon. In domestic law, some documents, such as the Fifth and Sixth Five-Year Programs and the Biosafety Law, have addressed this issue. The present paper aims to "study bioterrorism in international documents and domestic law" using descriptive-analytical method and data collection in a library-documentary method. The results showed in domestic law although positive steps have been taken, due to the lack of serious biological threats, the low speed of the legislature and the lack of a differentiated view, the mechanisms of combating biological terrorism not efficient and the Iranian legislature has not been convicted the Bioterrorism as an independent crime. Therefore, in order to determine the response to that behavior, it must adapted to other general criminal titles. In the international arena, the shortcomings and ambiguities in some international documents and the problem of verifying the performance of government’s, are the weaknesses of international standards in the field of biological weapons.